shortening leads to a limited

The telomere theory states that telomeric shortening leads to a limited number of cell divisions, after which there is a cessation of cell proliferation Night Comfort Review.

The immune theory gives a fundamental role to the immune system as a controller of the aging process, and that its defective function leads to incompatible changes with life Night Comfort Review, such as some types of cancer.

The neuroendocrine theory postulates that abnormalities in the hypothalamic pituitary adrenal axis lead to damage in the homeostasis of the body, with a decrease in the ability to survive.